Magnesium Stabilizes Telomeres - Dr. Carolyn Dean MD ND

Magnesium Stabilizes Telomeres

August 31, 2012

Here’s the abstract of a totally cool paper in Clin Interv Aging, 2012, called “Correcting magnesium deficiencies may prolong life.”

A word about “may.” Scientists will never own up to anything; they will always hedge their bets and say “may” instead of “will”. But I know magnesium Will prolong life.

So, go ahead and read the Abstract that mentions how magnesium even stabilizes telomeres. Teleomeres are all the range in antiaging circles. A telomere is a region of repetitive nucleotide sequences at each end of a chromosome which protects the end of the chromosome from deterioration.

“The International Space Station provides an extraordinary facility to study the accelerated aging process in microgravity, which could be triggered by significant reductions in magnesium (Mg) ion levels with, in turn, elevations of catecholamines and vicious cycles between the two. With space flight there are significant reductions of serum Mg that have been shown in large studies of astronauts and cosmonauts. The loss of the functional capacity of the cardiovascular system with space flight is over ten times faster than the course of aging on Earth. Mg is an antioxidant and calcium blocker and in space there is oxidative stress, insulin resistance, and inflammatory conditions with evidence in experimental animals of significant endothelial injuries and damage to mitochondria. The aging process is associated with progressive shortening of telomeres, repetitive DNA sequences, and proteins that cap and protect the ends of chromosomes. Telomerase can elongate pre-existing telomeres to maintain length and chromosome stability. Low telomerase triggers increased catecholamines while the sensitivity of telomere synthesis to Mg ions is primarily seen for the longer elongation products. Mg stabilizes DNA and promotes DNA replication and transcription, whereas low Mg might accelerate cellular senescence by reducing DNA stability, protein synthesis, and function of mitochondria. Telomerase, in binding to short DNAs, is Mg dependent. On Earth, in humans, a year might be required to detect changes in telomeres, but in space there is a predictably much shorter duration required for detection, which is therefore more reasonable in time and cost. Before and after a space mission, telomere lengths and telomerase enzyme activity can be determined and compared with age-matched control rats on Earth. The effect of Mg supplementation, both on maintaining telomere length and extending the life span, can be evaluated. Similar studies in astronauts would be fruitful.”

Sorry if this takes the glamour out of space travel but it does provide a great model for studying aging and validates the miracle of magnesium. My answer to aging is obviously to take magnesium. The various types I recommend you can find under Resources on my site. You can also take RnA Drops. I have a patent on the base ingredient of RnA Drops, which you can try for free to see if it resonates with you.

Carolyn Dean MD ND

The Doctor of the Future®

RESOURCES: Along the borders and in the links of my web site you can find my books, writings, and my call-in radio show. Email your questions to:

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