The Ageless Summit launches June 20, 2016 and runs for only 5 days with 4 speakers each day. My interview is on June 22. So, click on the link and join another information-packed Summit. In my interview with Bryan Adair, I wanted to highlight an amazing paper by my favorite magnesium researchers, Drs. Burton and Bella Altura. I don’t know how far I got in discussing the Altura’s work, so I will excerpt sections here from the next edition of The Magnesium Miracle.
Here’s what will appear in my 2017 Magnesium Miracle book on the topic of Aging. The current research on aging is firmly tied up in telomeres and finding a way to protect our telomeres has become the Holy Grail of longevity research. It should come as no surprise that magnesium is tightly wrapped up with telomeres. But the real shock is how few researchers are focusing on the miracle of magnesium in keeping telomeres from unraveling. Instead they are looking for drugs or formulating expensive supplements to save the telomeres – ignoring the solution that’s right before their eyes.
Aging is documented in our DNA as year-by-year greater numbers of redundant telomere segments at the end of our chromosomes are nibbled away, eventually leaving the chromosome exposed. Telomere segments keep genes stable but shorten over time as cell division becomes less efficient, especially if the enzyme telomerase reverse transcriptase is deficient or not working properly. You don’t have to guess at what affects this enzyme – magnesium, of course. Telomerase reverse transcriptase is magnesium–dependent.
The title of the Altura’s paper is “Short-term magnesium deficiency downregulates telomerase, upregulates neutral sphingomyelinase and induces oxidative DNA damage in cardiovascular tissues: relevance to atherogenesis, cardiovascular diseases and aging.” You can find it freely available online and you should read it in its entirety. The paper’s discussion section is especially important showing how telomeres are damaged by a host of environmental factors, all of which are treatable and preventable by therapeutic levels of magnesium. The paper is supported with 142 references and it is so brilliant that I was quite beside myself with excitement when I first read it.
In this study, healthy rats were tested for their magnesium levels. The animals were then divided into two groups. One group ate rat chow with standard amounts of magnesium; the other group was given chow with reduced magnesium. After 21 days, the telomerase levels had dropped a significant 70-88 percent in the low-magnesium group. Telomerase measured specifically in heart cells was similarly reduced. Markers for free radical damage to DNA were also increased. Free radicals shorten telomeres.
The title of the paper says “short-term” to indicate that it only took 21 days for this extensive damage to occur. In my clinical experience, most people who approach me with magnesium deficiency symptoms have suffered years – even decades of magnesium deficiency. In their conclusion, the Alturas say “We believe in view of the current report, and other works recently published by our labs, prolonged magnesium deficiency should be categorized as another epigenetic mechanism.” By epigenetic, they mean that magnesium deficiency has a definite effect on genes, and therefore on the vulnerable telomeres at the end of chromosomes.
In conclusion, please join The Ageless Summit and gather all the longevity tips you can AND be sure and take your ReMag, which is the most concentrated, non laxative, therapeutic magnesium available today and your single most important anti-aging nutrient.
Carolyn Dean MD ND
The Doctor of the Future®
SUMMITS: Women Against Cancer Summit launches on June 20, 2016 with Rebekah Lumley. I’ll post my date when it becomes available.
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