NSAIDs + Anticoagulants a Dangerous Combination - Dr. Carolyn Dean MD ND

NSAIDs + Anticoagulants a Dangerous Combination

July 25, 2018

Medscape announced their conclusion from a recent clinical investigation finding that “NSAIDs Plus Anticoagulants a Dangerous Combination” leading to major bleeding and stroke. Unfortunately, it’s common practice to put drugs on the market without identifying their interactions with other common drugs. And it’s only years afterward in what’s called “post marketing surveillance” that problems are identified.


70 million prescriptions are written each year for nonsteroidal anti-inflammatory drugs (NSAIDs). They harbor the many side effects. A common NSAID, Naproxen has an enormous list of 142 side effects. Here are a few of the most common ones.

* Stomach pain, heartburn, indigestion, nausea * Stomach ulcers * Bleeding tendency * Bleeding worse with aspirin
* Bruising * Headache, dizziness, drowsiness * Ringing in the ears * Allergic reactions: rashes, wheezing, and throat swelling * Liver or kidney problems * High blood pressure


Over the last few years, the FDA has approved four new oral anticoagulant drugs – Pradaxa (dabigatran), Xarelto (rivaroxaban), Eliquis (apixaban), and Savaysa (edoxaban). Like warfarin, all four blood thinners help reduce the overall risk of stroke related to atrial fibrillation but they also cause bleeding. And unlike warfarin, where bleeding can be reversed with Vitamin K – there is no antidote to stop the bleeding once it has started.

Now that doctors have these new anticoagulants they are all about diagnosing new cases of atrial fibrillation so they can prescribe them. But I’m sure they don’t ask their patients what other drugs they are using. They are going to have to start being more careful because anyone on anticoagulants is now being told to avoid NSAIDs.

Since it is more often senior citizens who are developing AFib (many due to magnesium deficiency), they also can have osteoarthritis (another magnesium deficiency condition) and use NSAIDs for inflammatory pain control. Instead of advising a well-absorbed magnesium like ReMag, I’m afraid they are now going to be offered addictive opioids since they are being warned off NSAIDs and since Tylenol is not an anti-inflammatory.

My recommendation is obvious – use magnesium (ReMag preferably) for possible magnesium deficient AFib and magnesium deficient osteoarthritis and the other 700-800 enzymatic biochemical reactions it can perform in the body.

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Carolyn Dean MD ND

The Doctor of the Future®

RESOURCES: Along the borders and in the links of my web site you can find my books, writings, and my call-in radio show. Email your questions to: questions@drcarolyndeanlive.com.

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