Longevity Through Cellular Nutrition
Maui ReSet Study
Reducing Biological Age and Pace of Aging with the Right Nutrients
The Goal is to Reduce Your Biological Age by Slowing the Pace of Aging with the Right Nutrients
Over six months on Maui, ten everyday people, ages 34 to 79, followed the same daily nutrient protocol. A finger prick blood test before and after the 6-month study measured Age and Health Factors via epigenetic methylation testing.
This page tells the whole story: what we did, what we saw, and how my fifty-year career led to the formulas at its center.
What we set out to observe
What I wanted to document
I wanted to do an in depth survey of my customer base to see how their health improved on my formulas. Our research director, who ran the Purdue ReMag Absorption Study in 2020 said it wouldn’t fly, we had to do a study with before and after testing. He was all fired up about the new epigenetic methylation testing and we realized that we could do a small pilot study right here in my own backyard.
The question was simple to ask, and I’ve been asking it for decades. When the body is given consistent, highly absorbable nutrients at the cellular level, we should see health benefits. And now with standardized epigenetic testing, we will be able to measure the biomarkers that track how a person is aging?
We chose a defined daily nutrient protocol. We recruited real people living real lives, with real stress and real health histories. And we measured them with an independent testing partner and received before and after reports.
The study at a glance
The core design choices behind the Maui ReSet pilot: who, how long, how it was measured, and what they took.
| Design | Uncontrolled observational pilot, not randomized, no control group |
| Duration | August 2025 to February 2026 (six months) |
| Participants | 10 adults, ages 34 to 79, from a farm store, a farmer’s market, and the wellness community on Maui |
| Clocks measured | OMICm Age (Harvard), Symphony Age (Yale’s 11 organ-system clock), and DunedinPACE (pace of aging) |
| Testing & compliance | Before-and-after testing was run by TruDiagnostic, an independent third-party lab, on its TruHealth and Advanced TruAge panels, so the results were not ours to grade. Adherence to the daily protocol was self-reported, alongside general healthy-eating guidance and no forced dietary changes. |
| Absorption | Picometer-sized, stabilized mineral ions (see our unique, ground-breaking ReMag Absorption Study, Purdue 2020), plus food-based vitamins and low-potency food-based methylated B vitamins, which tend to be well absorbed |
| Formulator | Dr. Carolyn Dean MD ND |
| Assistant | Julie Simon |
The bigger picture: where this testing is being used
In 2026, the large randomized COSMOS trial (n=958) reported that a daily multivitamin-mineral slowed the pace of aging by about four months over two years: independent evidence that multiple nutrients are tied to aging biology. Our pilot asks a sharper version of the same question: whether a fuller array of nutrients, delivered in highly-absorbable picometer ionic forms, can move that needle meaningfully in a far shorter window. The two studies use different epigenetic methylation clocks and very different designs, so they are not directly comparable. We never present ours as beating a randomized trial; we only set the parameters side by side and let them stand.
Download the Maui ReSet Research Study
The complete study as a PDF: design and methods, the participant data, and the appendix tables behind every figure on this page. 1.4 MB.
Download the whitepaper (PDF)What we saw, system by system
These are observed, cohort-level trends from a small pilot (not proof of efficacy), but the top-line movement was consistent across the group. And the clearest signal pointed inward: the organ-level clock (Yale’s Symphony Age) appeared to move more than the whole-body one. First the group-wide numbers below, then two ways to go deeper: system by system through the people who lived it, and pillar by pillar across the organ-systems.
The formulas, and the physician behind them
Every result on this page rests on the same seven formulas, taken daily for six months. Here is what they are, and why this particular set was chosen for a study about aging biomarkers.
The form the body can absorb
With minerals, the limit is rarely the dose. It is how much ever reaches a cell. Most mineral supplements are compounds the gut has to break apart first, and much of what you swallow passes straight through. The four liquid formulas here are picometer-sized, stabilized mineral ions, small enough to pass through the cell’s own mineral ion channels rather than waiting on digestion. The three capsule formulas are food-based for the same reason. ReMag is the one with independent laboratory work behind it, the Purdue ReMag Absorption Study of 2020.
The chemistry the clocks measure
An epigenetic clock does not read your minerals. It reads methylation, the pattern of chemical tags sitting on your DNA. Those tags are built from methyl groups derived from methylated B vitamins, which drive methylation happening constantly in every cell of the body to the tune of a billion to trillions of reactions every single second. It is a core background process required for life, touching almost every major physiological system rather than running a single isolated function Magnesium sits underneath all of it, a cofactor in 600 to 800 enzyme reactions including the ones that copy and maintain DNA. That is why this particular set was chosen for a study about aging biomarkers: it feeds the same chemistry the test reads.
Important disclosures
About the study. This content is for informational and educational purposes. The Maui ReSet Pilot Study is a real-world observational pilot (n=10) and is not a randomized controlled trial. Results are hypothesis-generating and should not be interpreted as clinical proof of efficacy.
All formulas described are dietary supplements that support the normal structure and function of the body. They are not intended to diagnose, treat, cure, or prevent any disease.
Dr. Carolyn Dean is the founder and formulator of the nutrient line used in this study and holds a creative and economic interest in those products. Biological-age testing was performed by TruDiagnostic, an independent testing partner. These statements have not been evaluated by the Food and Drug Administration. Always consult your healthcare provider before beginning any new dietary supplement or wellness program. Individual results vary.