Immune Resilience

Defense and Recovery

Immune Resilience

Lens: Immune

Immune resilience is your body’s capacity to defend against everyday threats and recover from them. Immune function tends to weaken with age. There is even a name for it – immunosenescence – and it leans heavily on nutrients, especially zinc and vitamin D, which tend to run low in older adults. If you top up your nutrients, you don’t have to experience immunosenescence. TruDiagnostic’s TruHealth panel reads immune markers and reports a percentile, where higher reflects a stronger immune system.

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Dr. Carolyn Dean, MD ND, from Total Body ReSet for Men
“People don’t know how good they can feel until they become saturated with nutrients.”
Dr. Carolyn Dean, MD ND, from Total Body ReSet for Men
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Participants improved their immune markers over six months. This was the category the group improved the least; several readings fell, which the study reports openly. When you read the participants’ stories, I’m sure you’ll be able to identify the people whose immune systems were heavily stressed. However, two participants posted some of the largest immune gains in the whole study.

Behind those numbers are ten everyday people, ages 34 to 79. Immune resilience was the toughest marker to shift in six months, and most readings did not rise. Two participants, however, climbed sharply – let’s look at Suzanne’s and Helen’s numbers.

Where it showed up

Pseudonyms, release gated
Representative portrait. Not a real participant.
Suzanne, 50
Study participant, retested at six months
38th 89th Immune marker
percentile
Biggest immune gain in the study

Suzanne’s immune marker rose from the 38th to the 89th percentile, the largest immune gain in the group. Over the same six months she also slowed her pace of aging and reported a brighter mood.

Measured by TruDiagnostic, an independent lab. Participants have been given pseudonyms.
Representative portrait. Not a real participant.
Helen, 70
Study participant, retested at six months
36th 70th Immune marker
percentile
Strong immune climb

Helen’s immune marker climbed from the 36th to the 70th percentile, part of the broad turnaround that made her the study’s strongest overall responder across several markers.

Measured by TruDiagnostic, an independent lab. Participants have been given pseudonyms.
The RnA ReSet nutrients behind Immune Resilience

Immunity runs on minerals, vitamins and a healthy gut, which the following foundational nutrients bring together. Pico Zinc Plus® leads, with D3K2 ReSet® and Flora ReVive® in support. Swipe to see each.

Lead formula
Pico Zinc Plus®

Pico Zinc Plus®

Balanced zinc and copper as highly-absorbed stabilized mineral ions. Zinc is the mineral that immune cells depend on most, and runs low in the older community.

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D3K2 ReSet®

D3K2 ReSet®

Vitamin D enhances the function of immune cells and regulates inflammatory responses. It helps produce antimicrobial proteins and promotes the development of regulatory T cells, which are essential for maintaining immune balance. Low vitamin D is among the most common nutrient shortfalls, especially in older adults and especially occurring in winter.

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Flora ReVive®

Flora ReVive®

A soil-based probiotic and antifungal for the gut, where much of the immune system resides. It is introduced in the second Phase of the ReSet and was not part of the original Maui ReSet Study. If it had been part of the study perhaps our participants’ immune systems would have become more resilient faster.

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Formulated by Dr. Carolyn Dean. Made and sold by RnA ReSet. Purchased on rnareset.com.

The science of nutrition and synergy

Immunity depends on nutrient sufficiency, and it tends to decline with age. Zinc is the clearest example. Zinc is essential for innate and adaptive immunity, and marginal zinc deficiency is common in older adults, contributing to immunosenescence, to the point that zinc deficiency is proposed as a link between immune aging and age-related disease. In a randomized trial, zinc supplementation raised zinc status and enhanced T cell function in older adults with low zinc. This is what Pico Zinc Plus® supplies. The Plus in the formula is copper, which is added because, over time, zinc can deplete copper levels and because copper on its own enhances immunity by supporting white blood cell production (neutrophils and macrophages).

The NIH Office of Dietary Supplements notes that vitamin D supports normal immune function, supplied here by D3K2 ReSet®.

Much of the immune system lies in the gut, a healthy gut community supports the body more broadly and is provided by Flora ReVive®.

The science above is about the nutrients and the strongest results occur in people who begin with nutrient deficiency. In our Maui ReSet Study, immune markers were the category that shifted the least, which may mean we should have supported the gut early on with Flora ReVive. We also acknowledge that the study was short and a longer study could have shown stronger immune markers.

Commonly asked questions

What is immune resilience, and why does it matter for aging?

Immune resilience is your body’s capacity to defend against threats and then recover. In the average population, immune function gradually weakens with age, a process called immunosenescence, which leaves older adults more vulnerable. Having optimum levels of the nutrients that immunity depends on is part of a healthy aging picture.

How does zinc support immunity?

Zinc is essential for immune cells to develop and function, and marginal zinc deficiency is common in older adults. Clinical trials show that correcting low zinc can improve T cell function. Pico Zinc Plus® supplies zinc balanced with copper, since the two need to be in a proper zinc: copper ratio of 10:1.

Did the Maui ReSet improve everyone’s immune markers?

As reported above not everyone’s immune markers improved as much as we would like. Immune resilience was the category the group shifted least on. Only some participants improved and several readings fell. Six months may be a short window to influence immune changes. We report the full picture, including where the study did not show a broad shift.

What does the immune marker on a TruHealth report mean?

It is an epigenetic signature associated with immune biochemistry, reported as a percentile from 0 to 100 where higher is more favorable. A rising percentile suggests a more resilient profile. It is a trend to watch over time rather than a single reading.

Will these formulas boost my immune system or prevent illness?

The FDA does not allow such claims to be made. These foundational nutrients are supposed to be found in our diet; they are not drugs. They support the normal structure and function your immune system depends on to maintain healthy aging. Speak with your healthcare practitioner about any specific immune concerns you may have.

We focus on structure and function. These statements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease.